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Mega IgG2000: Targeted Toxin Binding & Gut Tissue Healing
>> How Immunoglobulins (Ig) Work
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Mega IgG2000 is a gentle toxin binder that works along with probiotics to enhance gut healing. Immunoglobulins (Ig) mop up and neutralize a range of disease-causing toxins from bacteria, mold and the environment, including C. difficile toxins A and B. They also reduce inflammation and intestinal damage.
IgG only targets disease-causing bacterial components and toxins inside the gut and will not absorb drugs, other supplements, foods or nutrients. It is best used along with MegaSporeBiotic. Because Mega IgG2000 binds bacterial and fungal toxins and die-off products, it can help to ease potential discomfort when starting high-powered probiotics, such as MegaSporeBiotic.
How Immunoglobulins Work
Immunoglobulin G (IgG), the most abundant antibody in the product, binds to a number of disease-causing bacteria, viruses, and fungi, as well as their toxic by-products. Binding these toxins will neutralize them and allow the immune system to safely remove them from the body. In addition to bacterial toxins like C. diff. toxins A and B, this Immunoglobulin also binds toxins from cell wall deficient mycoplasma species (L-forms) that are resistant to most antibiotic drugs*.
Unlike clays, charcoal and other popular binders that indiscriminately bind to a wide range of molecules and toxins, Mega IgG2000 specifically targets disease-causing bacterial components and toxins inside the gut. Toxins elicit an immune response inside your body, part of which is the production of antibodies, or immunoglobulins. These immunoglobulins specifically bind to unwanted toxins and remove them*.

Immunoglobulin antibodies have a chemical lock called an antigen-binding fragment. This lock only binds to a specific toxin that it is keyed to fit. The antibody can be fitted with any lock that’s needed, depending on which toxins need removed. The lock is very specific and can differentiate between thousands of different bacteria, yeast, mold, microbial toxins, allergens and viruses. Antibodies are saved by your immune system in case you are exposed to the same toxin again in the future. So immunoglobulins know precisely what to do when a potentially dangerous organism is caught entering your body
Shot Guns Versus Precision Snipers
Most toxin binding products containing clays, charcoal and similar ingredients work indiscriminately to bind a wide range of molecules and toxins. Such products work like a shot gun, strongly binding to anything they come into contact with. The trouble is, these broad-acting products also bind to medications, other supplements and to nutrients in your gut. This is why most toxin binder products must be taken on an empty stomach and at least one hour away from all drugs and supplements.
There is a time and place for traditional toxin binders like charcoal and clay. IgG and traditional binders work in different ways, have their own unique benefits and they complement each other well.
In contrast, immunoglobulins (Ig) selectively target gut pathogens and their toxins without binding to other things, such as foods or medications. The Mega IgG2000 product works more like a precision sniper rather than a shot gun. In other words, IgG only binds to harmful toxins and will not interfere with foods, nutrients, other supplements or any drugs you may be taking.
What’s Inside Mega IgG2000?

The key ingredients inside Mega IgG2000 include Immunoglobulin G (IgG), Immunoglobulin M (IgM), Immunoglobulin A (IgA), and Transferrin (aka Bovine Serum Albumin). Other ingredients include sunflower lecithin and vegetable capsule (cellulose and water).
Rather than being derived from mineral and herbal sources, this IgG is derived from edible bovine (beef) serum, also known as serum-derived bovine immunoglobulin/protein isolate (SBI). Mega IgG2000 is a good choice for long term maintenance, because it’s more targeted and discretionary in how it works than traditional toxin binders containing clays and charcoal.
Supplements containing serum-derived IgG bind to unwanted elements inside your GI system, sticking to them like glue. The IgG then pulls the toxins safely out of your body before they have a chance to damage the fragile lining of the intestines. Immunoglobulins reduce the toxic impact on the gut and immune system.
Mega IgG2000 Benefits
The serum-derived IgG in Mega IgG2000 binds to unwanted elements inside your GI system, sticking to them like glue. The IgG then pulls the toxins safely out of your body before they have a chance to damage the fragile lining of the intestines. Immunoglobulins reduce the toxic impact on the gut and immune system. Below are several benefits of Serum-Derived Immunoglobulins:
- Immunoglobulins are clinically proven to support immune health and digestive function.
- Gut infections and overgrowths: IgG protects against infections and binds to bacteria, fungi, mold, viruses and their associated toxins1. It binds inflammatory LPS (lipopolysaccharides) toxins, H. pylori (gram negative bacteria found in the stomach), mycotoxins, Staphylococcus, Salmonella, E. coli and other pathogenic bacteria.
- C. diff. toxins: IgG binds both C. difficile toxins A and B2, 3, 4.
- Irritable Bowel Syndrome (IBS) support: IgG improves pain and diarrhea and manages chronic loose and frequent stools5. Multiple studies show benefit for IBS management.
- Irritable Bowel Disease (IBD) support: Significantly improves symptoms of IBD6, 7, multiple studies show benefit for IBD management.
- SIBO support: IgG therapy can resolve diarrhea symptoms and allow for normal bowel function8.
- IgG supports a healthy gut mucosal layer and strengthens gut barrier function so fewer toxins enter the bloodstream.
- Mega IgG2000 is an easier and safer choice for long-term usage than traditional binding products. This is because Mega IgG2000 is highly targeted and will not absorb drugs, foods, other supplements or nutrients as traditional binders do.
Is Mega IgG2000 Right For You?
Mega IgG2000 is ideal for gut infections and any kind of gut dysbiosis. If you have C. diff. and are not taking a toxin binding supplement, such as G.I. Detox+, then Mega IgG2000 is an excellent addition to your infection recovery regimen. Even if you are already taking G.I. Detox+, Mega IgG2000 can be added to your regimen to provide broader and more complete toxin support. And unlike G.I. Detox+, Mega IgG2000 is safe to take with drugs, supplements and food and is a better choice for long-term ongoing usage.
Mega IgG2000 mops up and neutralizes microbial and environmental toxins, lowering the toxic burden in your gut. It’s ideal for G.I. symptom relief, including diarrhea, frequent loose stools, C. difficile infections, ulcerative colitis, Crohn’s disease or anyone needing to restore gut health.
If you're unsure which probiotics or toxin binder is best for you, then use the decision tree below to help you choose the best products to fit your unique needs, with the help of a holistic or natural healthcare professional:
NOTE: Get special pricing on Mega IgG2000 and related product packs further below.
Suggested Use Protocol
Mega IgG2000 is a well tolerated by most people. In fact, it can help relieve the mild symptoms sometimes caused by taking powerful probiotics for the first time, such as MegaSporeBiotic.
* PLEASE FOLLOW THE USE GUIDE BELOW, OR AS DIRECTED BY YOUR HEALTHCARE PROVIDER *
PLEASE follow the Probiotic Restoration Guide below
for best results with Mega IgG2000 for C. difficile:
Click here to open the Guide
Be sure to save document to your device for future reference.
Adults with Infections: We suggest starting with 4 capsules, 2 - 5 times per day, depending on the infection severity. For example, mild infections may start with 4 capsules 2 times per day. And severe infections may start with 4 capsules 5 times per day.
The starting amount is continued for two months, or until symptoms subside. Afterward, the amount can be slowly reduced over two weeks and then finally stopped, if desired.
Mega IgG2000 may also be used for long-term maintenance at a low usage level. We recommend 2 - 4 capsules 1 time per day for ongoing maintenance.
Diarrhea and Gut Discomfort?
For extra support with diarrhea, antibiotic-associated diarrhea and gut discomfort, consider adding RestorFlora probiotic along with MegaSporeBiotic.
RestorFlora is a special-purpose spore-probiotic that contains the beneficial yeast Saccharomyces boulardii. S. boulardii has proven benefits when it comes to C. difficile bowel disorders and supporting healthy bowel microflora during or after antibiotic use.
Follow the suggested usage instructions inside the Probiotic Restoration Guide above and use Mega IgG2000 along with MegaSporeBiotic for best results. Working with a knowledgeable healthcare professional is always recommended while taking Mega IgG2000 or any other supplement. Always consult your healthcare professional before starting any new supplement.
Get Mega IgG2000 Today
Mega IgG2000 is for short-term toxin binding infection support, as well as long term preventative maintenance. MegaSporeBiotic is for long-term digestive and immune support. RestorFlora is for short-term extra support with C. diff. diarrhea, antibiotic-associated diarrhea and gastrointestinal upset. Get the exact level of support you need with the following cost-saving kits:
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We’re Here to Support You
Michelle strives to provide you with the best value and personal assistance on the most effective products. Michelle and her staff are here to answer your questions, walk you through her protocols and methods and to provide ongoing support on your path to health.
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References:
1. Detzel CJ, Horgan A, Henderson AL, et al. Bovine immunoglobulin/protein isolate binds pro-inflammatory bacterial compounds and prevents immune activation in an intestinal co-culture model. PLoS one. 2015;10(4):e0120278. https://doi.org/10.1371/journal.pone.0120278. 1.
2. Crawford C., Panas R. Post-Infectious Irritable Bowel Syndrome with Functional Diarrhea Following C. difficile Infections: Case Studies of Responses Using Serum-Derived Bovine Immunoglobulin. Journal of Gastroenterology and Hepatology Research, Vol 4, No. 4 (2015). 3.
3. Silver S., Burnett, B. C. difficile Infection (CDI) Unresponsive to Antibiotics Resolved by Co-Administration of Serum Derived Bovine Immunoglobulin/ protein Isolate, a Nutritional Support Product: A Case Study. Advanced Research in Gastroenterology and Hepatology. Volume 6 Issue 2 - June 2017 DOI: 10.19080/ARGH.2017.06.555685. 4.
4. Ferm, S. Varadi, N. Fisher, C. et al. Serum-Derived Bovine Immunoglobulin as Novel Adjunct in Complicated Clostridium difficile Colitis Treatment May 2017 DOI:10.14309/crj.2017.64. 2.
5. Good L. Rosario R., Panas R. New therapeutic option for irritable bowel syndrome: Serum-derived bovine immunoglobulin. World J Gastroenterol 2015 March 21; 21(11): 3361-3366. 5.
6. Good L, Panas R. Case Series Investigating the Clinical Practice Experience of Serum-Derived Bovine Immunoglobulin/Protein Isolate (SBI) in the Clinical Management of Patients with Inflammatory Bowel Disease. Journal of Gastrointestinal &Digestive System. 2015; 5(2): 1-5. 6.
7. Shafran et al. Management of inflammatory bowel disease with oral serum-derived bovine Immunoglobulin. Therapeutic Advances in Gastroenterology. 2015; 8(6):331-9. 7.
8. Taxman, T, Panas R. Efficacy of Serum-derived Bovine Immunoglobulin/Protein Isolate (SBI) in Pediatric Patient with Acute Diarrhea Due to Small Intestinal Bacteria Overgrowth. EnteraHealth, Presented at Disease Week DDW® 2015 May 16 – 19, 2015 • Washington, DC. 8.